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"In our study, the women were 56 years old on average; they weren't as old.

Estrogen might lose its ability to act as positively in older women."Dr.

Anthony Grieco, a staff physician in obstetrics and gynecology at the Ochsner Clinic Foundation in New Orleans, said the researchers "did seem to get improvement in muscle mass of the heart" using HRT.

"It does sound as if low-dose (therapy) is of beneficial effect," he added.He noted that although the overall WHI results seem to r...

Baltimore lawyer Robert K.

Jenner, who is representing the plaintiff, says he has filed about a dozen such cases since the hormone replacement therapy litigation began in July 2002.

Nationally, the multidistrict litigation over The companies never ran their own studies to determine the long- term safety [of these drugs,] he said, asserting that dozens of studies have shown them to be dangerous.

The companies never explained to the public that the longer women stayed on hormone therapy, the greater the chances of developing breast cancer.

Jones' doctor prescribed hormone therapy drugs (or the generic medroxyprogesterone acetate) in the early 1990s.

The drug was then manufactured by all six of the defendants, i.e., the New Jersey- based Wyeth Inc.

and Pharmacia & Upjohn; Pennsylvania-based Wyeth Pharmaceuticals Inc.; Pfizer Inc.

and Barr Laboratories Inc.

of New York; and the Michigan-based Greenstone Ltd.

(Pharmacia & Upjohn was absorbed into Pfizer in 2003).

In 1995, Jones' doctor prescribed Wyeth's She took